Duchenne muscular dystrophy Clinical trials Immunogenicity inflammation gene therapy AAV Quality control Ectopic expression Innate immunity Adenoviridae/immunology Adeno-associated virus Humoral immunity Air tamponade Discriminant analysis Vector Fluid-air exchange Click chemistry Animals Assembly-activating protein ABCA4 CD8 + T lymphocytes Intravitreal Bioorthogonality Intrathymic gene transfer Gene Therapy Bioconjugates DMD Animal model Impurities AUC High-throughput technology Eye surgery Immunogenicity Exercise Infectivity AAV vector Genes Identity assay Tolerance Homopolymers GRMD dog In vivo Mice Engineering Immunosuppression Dystrophin Dynamin 2 Baculovirus expression vector DMDmdx rat Antibodies/immunology/metabolism CNS Gene-therapy AAV Congenital amaurosis Childhood blindness Capsid thermostability Acute treatment Baculovirus Age GC-content Immunomodulation Capsid thermal stability Crigler–Najjar Syndrome Clinical trial Inflammation Capsid assembly Gait assessment Manufacturing Identity CMC Beta-subunit Gene transfer High-throughput sequencing AAP Antibody responses Duchenne Cell–virus interaction Intra-cerebrospinal fluid injection Analytical ultracentrifugation Immune response Homologous recombination Homogeneity Inherited retinal dystrophies Dose study Treg Accelerometry Gene Transfer Cell therapy AAV vectors Cone photoreceptors Capsid Immune responses Calcium Centronuclear myopathy B-Lymphocytes/immunology/metabolism Exon skipping Human-monocyte-derived dendritic cells GRMD Gene therapy Adenoassociated viral vector Cerebellum Skeletal muscle Insect cells